Penn Image Computing and Science Laboratory

Software

PICSL develops and distributes open-source software for medical image analysis.

ITK-SNAP
ITK-SNAP

SNAP is a software application used to segment structures in 3D medical images. It provides semi-automatic segmentation using active contour methods, as well as manual delineation and image navigation. In addition to…

ANTs
ANTs

Advanced Normalization Tools (ANTs) extracts information from complex datasets that include imaging. ANTs development is led by Brian Avants and supported by other researchers and developers at PICSL and other…

Camino
Camino

Camino is an open-source toolkit for diffusion MRI simulation and image processing. The PICSL contribution to the tool is led by Philip Cook and focuses on image reconstruction pipelines and tractography. See the Camino…

HistoloZee
HistoloZee

HistoloZee is a tool that integrates histology reconstruction, MRI co-registration, and manual segmentation tools in an easy-to-use and intuitive interface. HistoloZee permits real-time interaction with complex and…

ASHS
ASHS

ASHS stands for “Automatic Segmentation of Hippocampal Subfields.” Here is what it does: - Automatically labels hippocampal subfields and medial temporal lobe cortices in MRI - Uses T1-weighted and T2-weighted MRI to…

LESYMAP
LESYMAP

Lesymap uses univariate and multivariate methods to map functional regions of the brain that, when lesioned, cause specific cognitive deficits. All is required is a set of Nifti images with the lesion of each subject…

LINDA
LINDA

An R toolkit for automatic segmentation of chronic stroke lesions. LINDA uses hierarchical predictions from low to high resolution, to achieve an iterative improvement of the segmentation. Relies on ANTsR for image…

TLEprediction
TLEprediction

TLEprediction is a small tool that uses R and Matlab to achieve the prediction of seizure onset laterality in patients with temporal lobe epilepsy. The tools uses three PET asymmetries to achieve the prediction and has…