I am an Assistant Professor of Radiology and Bioengineering with interest in developing methods for computational image analysis, anatomical shape modeling, and interactive visualization to guide surgical interventions. Specifically, my work has focused on modeling heart valve morphology and dynamics in 3D echocardiography for risk stratification and planning of heart valve repair surgery. The goal is to use automated image analytics to predict surgical outcomes, to inform development of surgical guidelines, and to advance minimally invasive therapies for the treatment of cardiovascular disease.
Research Areas
3D/4D segmentation and modeling of heart valves in echocardiographic images, with applications to surgical treatment of valvular regurgitation
- Semi-automated and fully automated segmentation of the mitral leaflets in 3D echocardiographic images
- Segmentation of the aortic valve apparatus, including the aortic root and tricuspid and bicuspid aortic valves
Integration of methods for image segmentation, shape representation, and biomechanical modeling
- Prediction of mitral leaflet stress distributions using patient-specific image-derived models of the mitral valve
Meshing and analysis of 3D anatomical shapes
- Statistical analysis of “normal” mitral annular geometry
- Automated meshing of the placenta in 3D ultrasound
3D printing of anatomical shapes in medical images
Positions
- Assistant Professor of Radiology, Perelman School of Medicine
- Core Faculty Member, Penn Center for Biomedical Image Computing and Analysis (CBICA)
- Faculty Member, Penn Cardiovascular Institute
- Core Faculty Member, Penn Institute for Computational Sciences (PICS)
Member of the Bioengineering graduate group.
Education
- Certificate, Biomedical Informatics, University of Pennsylvania, 2018
- Ph.D., Bioengineering (Biomedical Imaging and Informational Sciences), University of Pennsylvania, 2013, as part of the HHMI-NIBIB Interfaces Program
- B.S., Physics (Honors) and Anthropology, The College of William and Mary, 2007